{"id":965,"date":"2025-10-26T16:17:53","date_gmt":"2025-10-26T16:17:53","guid":{"rendered":"https:\/\/idpin.cnc.uc.pt\/?page_id=965"},"modified":"2026-01-09T11:27:11","modified_gmt":"2026-01-09T11:27:11","slug":"unravelling-brain-disorders-molecular-and-cellular-mechanisms-from-development-to-degeneration","status":"publish","type":"page","link":"https:\/\/idpin.cnc.uc.pt\/?page_id=965","title":{"rendered":"Unravelling Brain Disorders: Molecular and Cellular Mechanisms from Development to Degeneration"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"965\" class=\"elementor elementor-965\">\n\t\t\t\t<div class=\"elementor-element elementor-element-40725a1 e-flex e-con-boxed e-con e-parent\" data-id=\"40725a1\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-0e3a88d e-con-full e-flex e-con e-child\" data-id=\"0e3a88d\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-74743ab elementor-widget elementor-widget-heading\" data-id=\"74743ab\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">idpIN Courses 2025\/2026 - Unravelling Brain Disorders: Molecular and Cellular Mechanisms from Development to Degeneration\n<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-d8fe5eb e-con-full e-flex e-con e-child\" data-id=\"d8fe5eb\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-80f7185 elementor-widget elementor-widget-text-editor\" data-id=\"80f7185\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"color: #e1ad02;\"><strong>Organized by<\/strong><\/span><br \/>CNC-UC\/CIBB<\/p><p><strong><span style=\"color: #e1ad02;\">Date &amp; Time<\/span><\/strong><br \/>19\/01\/2026 &#8211; 23\/01\/2026<\/p><p><strong><span style=\"color: #e1ad02;\">Location<\/span><\/strong><br \/>CNC-UC, Polo I, Faculty of Medicine Building, 1st and 2nd floor<\/p><p><strong><span style=\"color: #e1ad02;\">Registration<\/span><\/strong><br \/>Mandatory<\/p><p>Deadline: 12\/01\/2026<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-d70320c e-flex e-con-boxed e-con e-parent\" data-id=\"d70320c\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-7e7c642 elementor-widget elementor-widget-button\" data-id=\"7e7c642\" data-element_type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/docs.google.com\/forms\/d\/e\/1FAIpQLSekWuRXjJcV1BR3OjCA9-PRK1zkGlJU42UX6kGE5VsvyHhROA\/viewform\" id=\"Register\" target=\"_blank\" rel=\"noopener\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Register<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-11a5926 e-flex e-con-boxed e-con e-parent\" data-id=\"11a5926\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-cdae048 e-con-full e-flex e-con e-child\" data-id=\"cdae048\" data-element_type=\"container\">\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-d178672 e-grid e-con-boxed e-con e-parent\" data-id=\"d178672\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-7a0df8f elementor-widget elementor-widget-heading\" data-id=\"7a0df8f\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Coordination<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-a167ce7 e-grid e-con-full e-con e-child\" data-id=\"a167ce7\" data-element_type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-691b089 e-grid e-con-full e-con e-child\" data-id=\"691b089\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-0029a39 elementor-widget elementor-widget-image\" data-id=\"0029a39\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"300\" height=\"300\" src=\"https:\/\/idpin.cnc.uc.pt\/wp-content\/uploads\/2025\/11\/ana-cristina-rego.webp\" class=\"attachment-large size-large wp-image-967\" alt=\"\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-ce68785 elementor-widget elementor-widget-text-editor\" data-id=\"ce68785\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><a href=\"https:\/\/cnc.uc.pt\/pt\/people\/a-rego\" target=\"_blank\" rel=\"noopener\"><b>Ana Cristina Rego<\/b><\/a><\/p><p><span style=\"color: #000000;\">CNC-UC\/CIBB &amp; FMUC<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-89a34a4 e-grid e-con-full e-con e-child\" data-id=\"89a34a4\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-b14c48b elementor-widget elementor-widget-image\" data-id=\"b14c48b\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"300\" height=\"300\" src=\"https:\/\/idpin.cnc.uc.pt\/wp-content\/uploads\/2025\/11\/claudia-pereira.webp\" class=\"attachment-large size-large wp-image-968\" alt=\"\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-c97bade elementor-widget elementor-widget-text-editor\" data-id=\"c97bade\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><a href=\"https:\/\/cnc.uc.pt\/pt\/people\/c-pereira-1\" target=\"_blank\" rel=\"noopener\"><b>Cl\u00e1udia Frag\u00e3o Pereira<\/b><\/a><\/p><p><span style=\"color: #000000;\">CNC-UC\/CIBB &amp; FMUC<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-c5eb8ab e-grid e-con-full e-con e-child\" data-id=\"c5eb8ab\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-0406f84 elementor-widget elementor-widget-image\" data-id=\"0406f84\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"300\" height=\"300\" src=\"https:\/\/idpin.cnc.uc.pt\/wp-content\/uploads\/2025\/11\/sandra-cardoso.webp\" class=\"attachment-large size-large wp-image-969\" alt=\"\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-7614936 elementor-widget elementor-widget-text-editor\" data-id=\"7614936\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><a href=\"https:\/\/cnc.uc.pt\/pt\/people\/s-cardoso-2\" target=\"_blank\" rel=\"noopener\"><b>Sandra Morais Cardoso<\/b><\/a><\/p><p><span style=\"color: #000000;\">CNC-UC\/CIBB &amp; FMUC<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-1198761 e-flex e-con-boxed e-con e-parent\" data-id=\"1198761\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-28208d3 e-con-full e-flex e-con e-child\" data-id=\"28208d3\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-18592a9 elementor-widget elementor-widget-image\" data-id=\"18592a9\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"215\" src=\"https:\/\/idpin.cnc.uc.pt\/wp-content\/uploads\/2025\/10\/idpIN_Website-background_2025.01.22-08.png\" class=\"attachment-large size-large wp-image-812\" alt=\"\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-ef22fda e-con-full e-flex e-con e-child\" data-id=\"ef22fda\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-8b8b00c elementor-widget elementor-widget-image\" data-id=\"8b8b00c\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"215\" src=\"https:\/\/idpin.cnc.uc.pt\/wp-content\/uploads\/2025\/10\/idpIN_Website-background_2025.01.22-08.png\" class=\"attachment-large size-large wp-image-812\" alt=\"\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-209611c e-con-full e-flex e-con e-child\" data-id=\"209611c\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-98e5854 elementor-widget elementor-widget-image\" data-id=\"98e5854\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"215\" src=\"https:\/\/idpin.cnc.uc.pt\/wp-content\/uploads\/2025\/10\/idpIN_Website-background_2025.01.22-08.png\" class=\"attachment-large size-large wp-image-812\" alt=\"\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-d84717c e-flex e-con-boxed e-con e-parent\" data-id=\"d84717c\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-e72fbe0 elementor-widget elementor-widget-text-editor\" data-id=\"e72fbe0\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h3 style=\"text-align: left;\"><span style=\"color: #821f3c;\"><strong>Aim<\/strong><\/span><\/h3><p>This interdisciplinary PhD course offers an in-depth exploration into the molecular and cellular mechanisms underlying neurodevelopmental, neuropsychiatric, and neurodegenerative disorders. Designed for advanced students and researchers, the course explores how genetic mutations, epigenetic changes, immune dysfunction, and environmental factors contribute to brain pathology across the lifespan. The course covers a wide range of disorders, including autism spectrum disorder (ASD), schizophrenia (SCZ), Parkinson&#8217;s disease (PD), Alzheimer&#8217;s disease (AD), and polyglutamine (polyQ) disorders, as Huntington&#8217;s disease (HD). Despite the clinical diversity of these disorders\u2014from early-onset ASD to late-onset AD, they converge on several core biological mechanisms, including synaptic dysfunction, mitochondrial deregulation, protein aggregation, immune dysregulation, microbiota signaling, and gene\u2013environment interactions. These shared pathways open opportunities for cross-disorder biomarkers and broad-spectrum therapeutic strategies. Through a combination of lectures and critical analysis of current literature, participants will gain a comprehensive understanding of the latest research techniques and therapeutic strategies aimed at combating these debilitating diseases. The course aims to equip students with a deep understanding of converging and disease-specific molecular pathways in brain disorders and how they inform translational research.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-5e57d8b e-flex e-con-boxed e-con e-parent\" data-id=\"5e57d8b\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-2afa7df elementor-widget elementor-widget-text-editor\" data-id=\"2afa7df\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h3 style=\"text-align: left;\"><span style=\"color: #821f3c;\"><strong>Program<\/strong><\/span><\/h3><p>Available <a href=\"https:\/\/drive.google.com\/file\/d\/1wW68UJFsBQT44HzIYmAhk1_XbNqRGAeR\/view?usp=sharing\" target=\"_blank\" rel=\"noopener\">here.<\/a><\/p><p>More info <a href=\"https:\/\/cnc.uc.pt\/pt\/pdbeb\/beb-advanced-courses\/pdbeb-courses-20252026-unravelling-brain-disorders-molecular-and-cellular-mechanisms-from-development-to-degeneration-1\" target=\"_blank\" rel=\"noopener\">here<\/a>.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>idpIN Courses 2025\/2026 &#8211; Unravelling Brain Disorders: Molecular and Cellular Mechanisms from Development to Degeneration Organized byCNC-UC\/CIBB Date &amp; Time19\/01\/2026 &#8211; 23\/01\/2026 LocationCNC-UC, Polo I, Faculty of Medicine Building, 1st and 2nd floor RegistrationMandatory Deadline: 12\/01\/2026 Register Coordination Ana Cristina Rego CNC-UC\/CIBB &amp; FMUC Cl\u00e1udia Frag\u00e3o Pereira CNC-UC\/CIBB &amp; FMUC Sandra Morais Cardoso CNC-UC\/CIBB &amp; [&hellip;]<\/p>\n","protected":false},"author":5,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-965","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/idpin.cnc.uc.pt\/index.php?rest_route=\/wp\/v2\/pages\/965","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/idpin.cnc.uc.pt\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/idpin.cnc.uc.pt\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/idpin.cnc.uc.pt\/index.php?rest_route=\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/idpin.cnc.uc.pt\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=965"}],"version-history":[{"count":16,"href":"https:\/\/idpin.cnc.uc.pt\/index.php?rest_route=\/wp\/v2\/pages\/965\/revisions"}],"predecessor-version":[{"id":1195,"href":"https:\/\/idpin.cnc.uc.pt\/index.php?rest_route=\/wp\/v2\/pages\/965\/revisions\/1195"}],"wp:attachment":[{"href":"https:\/\/idpin.cnc.uc.pt\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=965"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}